3D Bio-Printed HNSCC (Head and neck squamous cell carcinoma) in vitro model for biomedical applications
نویسندگان
چکیده
The tumor microenvironment (TME) greatly influences the proliferation and progression of HNSCC. Hence, an in depth understanding vivo TME is crucial recapitulating like pathophysiology vitro, still remains a challenge. 3D bioprinted models are increasingly researched on due to their ability precisely replicate cellular organization as seen vivo. This project attempts HNSCC vitro via bio printing technique.
منابع مشابه
MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
MicroRNAs (miRNAs) are small, noncoding RNAs which regulate cell differentiation, proliferation, development, cell cycle, and apoptosis. Expression profiling of miRNAs has been performed and the data show that some miRNAs are upregulated or downregulated in cancer. Several studies suggest that the expression profiles of miRNAs are associated with clinical outcomes. However, the set of miRNAs wi...
متن کاملAbbreviations: HPV: Human Papillomavirus; TSCC: Tonsillar Squamous Cell Carcinoma; HNSCC: Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) encompasses a multitude of cancer types, arising from the mucosal lining of the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. Alcohol and tobacco are well-recognized pre-disposing factors for these cancers. Several Nordic countries (Denmark [1], Sweden [2][3], Finland [4]), the United States [5-8] and Australia [9],...
متن کاملEpithelial-Mesenchymal Transition and Inflammation in Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) represents a large majority of cancers arising from the head and neck, especially the oral cavity. Despite advances in therapy, the five-year survival rate remains low due to the number of patients presenting advanced stages of the disease. The role of epithelial-mesenchymal transition (EMT) in tumorigenesis in HNSCC remains unexplored. The current ...
متن کاملIncidence of Etiologic Factors in Squamous Cell Carcinoma of Head and Neck in Ahvaz
Introduction: Squamous cell carcinoma (SCC) is the most common head and neck malignancy. Smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. The aim of this study was determining the incidence of etiologic factors in head and neck SCC. Materials and Methods: This is a cross-sectiona...
متن کاملDensity of mast-cells and Microvessels Density in head and neck cutaneous Squamous Cell Carcinoma
Background and Aim: Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer. Mast cells may play a role in tumor progression and metastasis by increasing angiogenesis. The aim of this study was to investigate the role of mast cells by increasing angiogenesis in invasion of head and neck cutaneous squamous cell carcinoma. Materials and Methods: In this cross-sectional stud...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Laryngo-rhino-otologie
سال: 2022
ISSN: ['1438-8685', '0935-8943']
DOI: https://doi.org/10.1055/s-0042-1747070